Distance from Isle of Palms, South Carolina to Florence, South Carolina
The driving distance from Isle of Palms, South Carolina to Florence, South Carolina is 145.1 mi (233.5 km)
The straight-line (air) distance is approximately 60 mi (96.6 km)
Estimated travel time by road is 2 hours 16 minutes
We found 3 routes between Isle of Palms and Florence.
Available Routes
Route Directions
Get on I-526 W in Mount Pleasant from Palm Blvd and SC-517 N/Isle of Palms Con
Follow I-26 W and I-95 N to US-52 S/W Lucas St in Florence County. Take exit 164 from I-95 N
Follow US-52 S/W Lucas St and State Rd S-21-12 to your destination
Route Directions
Take SC-517 N/Isle of Palms Con to US-17 N/N Hwy 17 in Mount Pleasant
Follow SC-41 N to Old River Rd/State Rd S-21-57 in Florence County
Follow Old River Rd/State Rd S-21-57 and E National Cemetery Rd/State Rd S-21-13 to your destination in Florence
Route Directions
Take SC-517 N/Isle of Palms Con to US-17 N/N Hwy 17 in Mount Pleasant
Follow SC-41 N to County Rd S-45-45/Santee Rd in Williamsburg County
Continue on County Rd S-45-45/Santee Rd. Take County Rd S-45-219 and SC-377 N/Martin Luther King Jr Ave to US-52 N
Follow US-52 N to S Church St in Florence
Follow S Church St to your destination
Journey Details
Traveling from Isle of Palms, South Carolina to Florence, South Carolina covers 113 miles (182 km) in a north direction. This mixed highways and local roads, substantial route typically takes 2 hours 21 minutes under normal conditions.
Drivers have 3 route options between these locations (113-145 miles / 182-233 km). The primary route shown here saves 2 minutes compared to alternatives.
Journey Waypoints
Isle of Palms
Starting Point
Florence
Destination
