Distance from Simpson, Illinois to Independence, Mississippi
The driving distance from Simpson, Illinois to Independence, Mississippi is 250.3 mi (402.8 km)
The straight-line (air) distance is approximately 124.1 mi (199.7 km)
Estimated travel time by road is 3 hours 55 minutes
We found 3 routes between Simpson and Independence.
Available Routes
Route Directions
Get on I-57 S in Mounds Precinct from IL-147 W, IL-146 W and IL-37 S
Follow I-57 S and I-55 S to MS-306 E in Coldwater. Take exit 271 from I-55 S
Follow MS-306 E to Sycamore Rd in Independence
Route Directions
Get on I-57 S in Mounds Precinct from IL-147 W, IL-146 W and IL-37 S
Follow I-57 S, US-60 W and US-67 S to AR-135 S in Clay County
Follow AR-135 S to US 49 S in Paragould
Follow US 49 S, I-555 and I-55 S to MS-306 E in Coldwater. Take exit 271 from I-55 S
Follow MS-306 E to Sycamore Rd in Independence
Route Directions
Get on I-24 E in Vienna from IL-147 W
Follow I-24 E to Jack Paxton Dr in Paducah. Take exit 7 from I-24 E
Get on I-69 in Graves County from US-45 S
Continue on I-69 to Dyersburg. Take the US-51 S/US-412 E exit from US-51 S
Get on I-40 W in Brownsville from TN-54 S
Follow I-40 W and I-269 S to DeSoto County. Take exit 13 from I-269 S
Take MS-305 S to Sycamore Rd in Independence
Journey Details
Traveling from Simpson, Illinois to Independence, Mississippi covers 249.3 miles (401 km) in a south direction. This highway, long-distance route typically takes 4 hours 3 minutes under normal conditions.
Drivers have 3 route options between these locations (249-302 miles / 401-486 km). The primary route shown here saves 1 hour and 1 minute compared to alternatives.
The route features scenic views. During evening weekday travel, expect evening rush hour with average speeds around 60 mph (97 km/h) .
Journey Waypoints
Simpson
Starting Point
Independence
Destination
