Distance from Keowee Plantation, South Carolina to Tishomingo, Mississippi
The driving distance from Keowee Plantation, South Carolina to Tishomingo, Mississippi is 405.5 mi (652.6 km)
The straight-line (air) distance is approximately 185.5 mi (298.6 km)
Estimated travel time by road is 6 hours 11 minutes
This route includes Toll roads along the way.
We found 3 routes between Keowee Plantation and Tishomingo.
Available Routes
Route Directions
Get on I-85 S from US-123 S/US-76 W and SC-11 S
Follow I-85 S, I-20 W and I-22 to MS-25 N in Itawamba County. Take exit 108 from I-22
Follow MS-25 N to Trace St in Tishomingo
Route Directions
Get on I-85 S from US-123 S/US-76 W and SC-11 S
Follow I-85 S, I-20 W and I-65 N to AL-157 N in Cullman. Take exit 310 from I-65 N
Follow AL-157 N, US-72 W and Natchez Trace Pkwy to Trace St in Tishomingo
Route Directions
Follow Queen Annes Ln and Hwy 28 S E to US-123 S/US-76 W
Take SC-11 S, I-85 S, I-75 N, GA-140 W and US-27 N to GA-48 W in Summerville
Continue on GA-48 W to Hammondville
Get on US-72 W in Scottsboro from AL-40 W
Continue on US-72 W. Take I-565 W, AL-20 W and US-72 W to MS-30 W in Tishomingo County. Take the exit toward Booneville from Natchez Trace Pkwy
Continue on MS-30 W. Drive to Trace St in Tishomingo
Journey Details
Traveling from Keowee Plantation, South Carolina to Tishomingo, Mississippi covers 388.4 miles (625 km) in a west direction. This highway, long-distance route typically takes 6 hours 36 minutes under normal conditions.
Drivers have 3 route options between these locations (388-413 miles / 625-664 km). The primary route shown here saves no time compared to alternatives.
The route features toll sections. During night weekday travel, expect minimal traffic congestion with average speeds around 62 mph (100 km/h) .
Journey Waypoints
Keowee Plantation
Starting Point
Tishomingo
Destination