Distance from Middletown, Ohio to Clayton, Ohio
The driving distance from Middletown, Ohio to Clayton, Ohio is 33.3 mi (53.7 km)
The straight-line (air) distance is approximately 15 mi (24.1 km)
Estimated travel time by road is 46 minutes
We found 3 routes between Middletown and Clayton.
Available Routes
Route Directions
Take S Preble County Line Rd and U.S. Hwy 40 E to Talmadge Rd in Clayton
Route Directions
Get on I-75 N in Franklin Township from OH-122 E
Follow I-75 N and I-70 W to Brookville Salem Rd in Clay Township. Take exit 24 from I-70 W
Continue on Brookville Salem Rd. Take W Salem St to Talmadge Rd in Clayton
Route Directions
Take OH-4 N and Diamond Mill Rd to Talmadge Rd in Clayton
Journey Details
Traveling from Middletown, Ohio to Clayton, Ohio covers 25.6 miles (41 km) in a north direction. This mixed highways and local roads, moderate route typically takes 38 minutes under normal conditions.
Drivers have 3 route options between these locations (26-45 miles / 41-72 km). The primary route shown here saves 11 minutes compared to alternatives.
Journey Waypoints
Middletown
Starting Point
Clayton
Destination