Distance from Sycamore, Missouri to Cleburne, Illinois
The driving distance from Sycamore, Missouri to Cleburne, Illinois is 281.7 mi (453.3 km)
The straight-line (air) distance is approximately 122 mi (196.4 km)
Estimated travel time by road is 4 hours 29 minutes
We found 3 routes between Sycamore and Cleburne.
Available Routes
Route Directions
Get on US-60 E/US-63 S in Willow Springs from MO-181 N
Follow US-60 E and I-57 to IL-149 W in West Frankfort. Take exit 65 from I-57
Follow IL-149 W and IL-148 N to Renfro Lake Rd in Six Mile Township
Route Directions
Get on US-60 E/US-63 S in Willow Springs from MO-181 N
Follow US-60 E and I-55 N to MO-74 E/Shawnee Pkwy in Cape Girardeau
Take IL-146 E, IL-127 N and IL-149 E to Renfro Lake Rd in Six Mile Township
Route Directions
Take MO-181 N and State Hwy CC to US-63 S/Jan Howard Expy in West Plains
Follow MO-142 E to US-160 E in West Doniphan Township
Take US-60 E and I-57 to IL-149 W in West Frankfort. Take exit 65 from I-57
Follow IL-149 W and IL-148 N to Renfro Lake Rd in Six Mile Township
Journey Details
Traveling from Sycamore, Missouri to Cleburne, Illinois covers 275.8 miles (444 km) in a east direction. This highway, long-distance route typically takes 4 hours 39 minutes under normal conditions.
Drivers have 3 route options between these locations (276-285 miles / 444-458 km). The primary route shown here saves 9 minutes compared to alternatives.
The route features scenic views. During evening weekday travel, expect evening rush hour with average speeds around 62 mph (100 km/h) .
Journey Waypoints
Sycamore
Starting Point
Cleburne
Destination